A Boeing 777 arrives at JFK and is on its way across the tarmac, when it suddenly stops dead. All window shades are pulled down. All lights are out. All communication channels have gone quiet. Crews on the ground are lost for answers, but an alert goes out to the CDC. Dr. Eph Goodweather, head of their Canary project, a rapid-response team that investigates biological threats, gets the call and boards the plane. What he finds makes his blood run cold.

In a pawnshop in Spanish Harlem, a former professor and survivor of the Holocaust named Abraham Setrakian knows something is happening. And he knows the time has come, that a war is brewing . . .

So begins a battle of mammoth proportions as the vampiric virus that has infected New York begins to spill out into the streets. Eph, who is joined by Setrakian and a motley crew of fighters, must now find a way to stop the contagion and save his city--a city that includes his wife and son--before it is too late.

Born in Guadalajara, Mexico, Guillermo del Toro is the director of the films Cronos, Mimic, The Devil's Backbone, Blade II, Hellboy I, Hellboy II, and Pan's Labyrinth, which garnered enormous critical praise worldwide and won three Academy Awards.

Chuck Hogan is the author of several acclaimed novels, including Devils in Exile and Prince of Thieves, which won the 2005 Hammett Award , was called one of the ten best novels of the year by Stephen King, and was the basis of the motion picture The Town.